Search on: IMMUNOGLOBULIN IDIOTYPES 
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Descriptor English:   Immunoglobulin Idiotypes 
Descriptor Spanish:   Idiotipos de Inmunoglobulinas 
Descriptor Portuguese:   Idiotipos de Imunoglobulinas 
Synonyms English:   Idiotype, Immunoglobulin
Immunoglobulin Idiotype
Idiotypes, Immunoglobulin  
Tree Number:   D12.644.541.500.745
D12.776.124.486.485.680.745
D12.776.124.790.651.680.745
D12.776.377.715.548.680.745
D23.050.550.750
G02.111.570.060.425.580
G12.500.450
Definition English:   Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains. 
Pharmacological Action:   Immunologic Factors
 
History Note English:   79 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   7313 
Unique Identifier:   D007130 

Occurrence in VHL:
 

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